
Instead, they may struggle with fatigue, low drive, anxiety or depression, and brain fog. In fact, many people who have imbalances like SIBO or Leaky Gut Syndrome don’t seem to have any digestive issues at all. It’s important to note that gut issues don’t always present with obvious digestive symptoms. In my clinical experience, adrenal fatigue symptoms are often caused by what’s going on in the gut. They’re often hard to pinpoint, and their causes can be elusive. Symptoms may include things like tiredness, brain fog, lack of motivation, or frequent headaches. The symptoms that we associate with adrenal fatigue tend to be what we refer to as “nonspecific.” This means that they are somewhat vague and could be symptoms of many different conditions. But the adrenal fatigue theory can end up distracting us from what’s really going on and can get in the way of effective treatment. Symptoms commonly associated with adrenal fatigue are real and worthy of being addressed seriously. In concluding that adrenal fatigue is not a valid diagnosis, though, we want to be careful not to throw out the baby with the bathwater. In contrast, Addison’s Disease, or primary adrenal insufficiency, is a true medical condition in which the adrenal glands are chronically unable to produce sufficient cortisol and aldosterone. On the whole, endocrinologists don’t support the adrenal fatigue theory.


This calls into question the idea that stress directly impacts adrenal function and/or cortisol production.


However, high-quality research simply has not been able to prove that adrenal fatigue is real. Eventually, this renders them unable to produce sufficient cortisol. The theory behind adrenal fatigue is essentially that with prolonged or chronic stress exposure, the adrenal glands become overworked and overtired. The adrenal glands are responsible for several hormonal functions, including releasing cortisol in response to stress.
